Many people want to look younger and more beautiful. In the field of cosmetic surgery for breast augmentation and corrective treatment of wrinkles and sags, many operations have recently been performed based on technical advances, and there has been a steady increase in the demand for surgery.
Seishin Regenerative Medicine Center applies regenerative medicine, which maximizes the potential for self-renewal, in the field of cosmetic surgery and works to establish a new therapeutic system providing safe cosmetic medicine of high quality.

Adipose tissue-derived stem cells (ADSC) were discovered in 2001 by Dr. Mark Hedrick, the founder of US Cytori Therapeutics, and are a type of adult stem cell present in subcutaneous adipose tissue. The discovery heralded a significant development in regenerative medicine. Transplantation of adipose tissue-derived stem cells harvested from the patient’s own adipose tissue now draws global attention, and the technology is being translated into clinical practice. Cosmetic Surgery Seishin applies the technology for transplantation of adipose tissue-derived stem cells to breast augmentation, anti-aging therapy, and breast reconstruction, thereby providing cosmetic regenerative medicine of greater efficacy and safety.

In the field of cosmetic surgery, Cosmetic Surgery Seishin was the first in the world to introduce the Celution™ System, which allows extraction of stem cells from adipose tissue. This system was developed by Cytori Therapeutics, which was founded by Dr. Mark Hedrick who discovered adipose tissue-derived stem cells. The system automates the cleaning of adipose tissue and cell separation and extracts a consistent quality and volume of stem cells in a short time. In the field of plastic surgery, transplantation of adipose tissue-derived stem cells with the Celution™System is performed at Kyushu University Hospital in Beppu. In addition, a clinical study of the system for breast reconstruction was conducted under the supervision of Keizo Sugimachi, director of Kyushu Central Hospital (professor emeritus at Kyushu University Faculty of Medicine), and Cosmetic Surgery Seishin General Director Kamakura participated in the study as a project member.

Clinical application of the Celution™System has started in many countries around the world, and the system is used clinically in medical institutions in Italy, Spain, and other countries. The introduction of this advanced system is based on an agreement between Cosmetic Surgery Seishin, a regenerative medicine-minded institution led by General Director Kamakura, and Cytori Therapeutics, which has long known of the activities of General Director Kamakura, such as participation in the Kyushu Central Hospital’s project in Japan.

We perform Celution™ Breast Augmentation, a procedure for regenerative medicine involving transplantation of adipose tissue-derived stem cells with the use of the Celution™System. Previous breast augmentation by injection of a woman’s own fat has a fat graft survival (retention) of 30% to 50%. In contrast, transplantation of adipose tissue-derived stem cells with its unique mechanism produces a high graft survival of 80% to 90% and allows semi-permanent maintenance of breast conditions after injection. With the use of adipose tissue collected from each woman, Celution™Breast Augmentation (transplantation of adipose tissue-derived stem cells) represents a highly safe treatment with no concern for rejection. With the proven track record in fat injection and relevant technical expertise, Cosmetic Surgery Seishin is the world’s first provider of Celution™Breast Augmentation (transplantation of adipose tissue-derived stem cells).

Cosmetic Surgery Seishin has different types of anti-aging procedures on the basis of regenerative medicine. Celution™ Rejuvenation Therapy (transplantation of adipose tissue-derived stem cells) is provided to pump up the depressed areas in the cheeks or around the eyes for improvements by injecting a mixture of the patient’s own fat and adipose tissue-derived stem cells harvested with the Celution™System. Because of the unique action of stem cells, this therapy produces fat graft survival higher than that achieved by conventional fat injection and allows durable, natural rejuvenation.

PRP Skin Regeneration Therapy, which uses platelet components (autologous platelet-rich plasma, PRP) collected from the patient’s blood, improves wrinkles and acne marks by utilizing the effect of platelets to potentiate your innate natural healing power and tissue reorganization potential. Cosmetic Surgery Seishin provides Premium PRP Skin Regeneration Therapy and New-PRP Skin Regeneration Therapy, which have much greater efficacy than PRP therapy.

Also available is New Derma Roller Therapy, in which a medical-grade roller is used to add micropunctures in the skin to activate skin collagen production and improve fine wrinkles and pores. All of these anti-aging procedures use the patient’s own tissue and maximize the innate ability for self-renewal to achieve rejuvenation. Regenerative medicine procedures at Cosmetic Surgery Seishin are characterized by greater efficacy with no risk of infections or allergic reactions.

Breast reconstruction aims to restore the appearance of the breast after surgery for breast cancer. In Breast reconstruction at Cosmetic Surgery Seishin, adipose tissue-derived stem cells are injected to restore the natural contour to the depressed breast cavity after partial resection of breast cancer. Stem cells function effectively to increase fat graft survival, with no concern for fat calcification (lump). Fully automated extraction of stem cells with the Celution™System is associated with shorter treatment time, reduced physical stress, and greater safety.

We perform HARG therapy, a cutting-edge treatment for hair regeneration on the basis of regenerative medicine. Developed through joint research involving several countries around the world, this therapy directly administers active substances (growth factors) into the scalp for medical hair regeneration. The therapy has been extensively used in Europe and South Korea, demonstrating hair growth, restoration, and safety. Along with the first introduction of HARG therapy (treatment for hair regeneration) in Japan, the Japan Hair Re-Generative Medical Association (chairman, Hirotaro Fukuoka MD) was established. The therapy is provided only at seventeen facilities of three clinics, including our clinics, which now participate in the association.

By establishing the Seishin Regenerative Medicine Center, we took a new step toward the integration of regenerative medicine and cosmetic medicine. For example, transplantation of adipose tissue-derived stem cells with the Celution™System is not merely a procedure for breast augmentation but is indicated for anti-aging treatment. Cosmetic Surgery Seishin actively incorporates regenerative medicine to establish a new therapeutic system and provide safe, effective anti-aging cosmetic medicine of high quality.

Seven clinics of Cosmetic Surgery Seishin nationwide are certified ISO 9001:2000, the international standards for quality management systems, and have a regular audit by a third-party institution to continue to provide quality medical care. This certifies that Cosmetic Surgery Seishin has a system to maintain a level of quality above the international standards, and even improve quality.